Statistical analyses
SPSS version.21.0 (SPSS Inc., Chicago, IL, USA) was used for statistical
analysis. The mean ± standard deviation or percentage (%) was used to
present the demographic and clinical data. The t-test for independent
samples was used to make comparisons between the training patients and
controls. For categorical data, Pearson’s chi-square test was applied.
Paired t-test was used to compare olfactory function in each group at
baseline and 12 weeks afterwards. Univariable linear regression analysis
was performed to investigate the relationship between changes in TDI
scores and age, sex, duration of disease, the severity of OD, LM score,
and OT. Factors with a p-value of <0.1 were subjected to
multivariable linear regression analysis. Multivariable linear
regression analysis was performed to investigate the relationship
between changes in TDI scores and sex, the severity of OD, and OT.