CONCLUSION
Among pregnant women with even milder forms of LVOTO/AS, increases in
cardiac volumes and AV gradients can be expected over the course of
pregnancy and to a greater degree than in pregnant women without
structural heart disease. Despite this, LV function and mechanics remain
in the normal range with LV function showing a trend to decline over the
course of pregnancy. No adverse cardiac events were observed in this
cohort. Significant LVOTO/AS is associated with reduced LV function and
mechanics as compared to mild LVOTO/AS, and in the event of clinically
relevant reduction, would likely account for adverse events. This
warrants further study with a focus on sequential LV function/mechanics
assessment over the course of pregnancy among those with only
significant LVOTO/AS.