Variable
|
Pre-Pregnancy
|
1st Trimester
|
2nd
Trimester
|
3rd Trimester
|
Post-
Partum
|
Avg
LVOTO/AS
|
Avg
controls
|
p^
|
Heart rate, bpm |
71 (11) |
69 (11) |
73 (12) |
77 (15) |
62
(7) |
77 (14) |
78 (15) |
0.78 |
LVEDD, mm |
45 (3) |
47 (5) |
49 (6) |
50 (6) |
45 (16) |
49
(6) |
45 (5) |
0.02 |
LVEDV, ml |
131 (11) |
134 (31) |
137 (26) |
141 (23) |
129
(36) |
138 (26) |
126 (26) |
0.88 |
LVESV, ml |
55 (11) |
53 (16) |
58 (14) |
63 (15) |
55 (11) |
60 (14) |
52 (12) |
0.03 |
LVEF, % |
59 (7) |
61 (6) |
57 (8) |
56 (6) |
59 (6) |
56 (7) |
57 (11) |
0.81 |
CO, l/min |
4.8 (2.0) |
5.6 (1.7) |
6.2 (5.5) |
5.9 (1.7) |
4.5
(1.7) |
5.7 (1.6) |
4.2 (1.5) |
0.001 |
LAV, ml |
43 (9) |
47 (7) |
53 (13) |
55 (12) |
53 (13) |
54
(12) |
53 (15) |
0.86 |
Mitral E/a |
1.5 (0.4) |
1.9 (0.8) |
1.7 (0.5) |
1.5 (0.4) |
1.8 (0.4) |
1.7 (0.5) |
1.7 (0.6) |
0.96 |
E’ medial |
10.3 (1.5) |
9.2 (1.7) |
10.2 (2.6) |
9.5 (2.4) |
9.0 (2.1) |
10.1 (2.7) |
10.7 (2.7) |
0.45 |
E’ lateral |
13.4 (3.6) |
13.7 (4.1) |
15.0 (3.4) |
13.0 (2.9) |
12.8 (3.0) |
14.5 (3.2) |
14.3 (4.7) |
0.89 |
LVOT PW |
5.1 (1.4) |
3.8 (1.7) |
6.6 (9.4) |
7.4 (9.8) |
4.1
(1.3) |
8.0 (10.8) |
4.6 (1.7) |
0.14 |
AV PG |
21.3 (14.7) |
23.5 (14.1) |
28.0 (19.8) |
26.0 (17.4) |
22.4 (17.1) |
27.4 (19.8) |
9.0 (2.7) |
<0.001 |
GLS |
-22.1 (1.8) |
-22.5 (2.2) |
-21.0 (2.5) |
-19.7 (3.1) |
-21.9 (2.4) |
-20.8 (2.6) |
-21.8 (1.8) |
0.10 |