Figure. 5. The shape effect of nanoparticles: A. Orientation of anisotropic nanoparticles increases membrane curvature. B. The particular dynamic process of anisotropic materials: orientation-wrapping-reorientation, reproduced from Reference19 with permission from The Royal Society of Chemistry. C. Comparison of the endocytosis efficiency of isotropic nanoparticles and that of anisotropic nanoparticles, reproduced from Reference59 with permission from The Royal Society of Chemistry. D. The process in which deformable spherical nanoparticles are wrapped by cell membranes and deform into asymmetrically shape, reproduced from Reference26 with permission from The Royal Society of Chemistry.