2.3 Evaluation of the ability to induce IL-4
The IL4pred tool (https://webs.iiitd.edu.in/raghava/il4pred/) was used to calculate the ability of epitopes to induce IL-4 secretion by Th2 cells, and a hybrid prediction method consisting of support vector machine and motif was selected. The support vector machine threshold was selected as 0.2 [22].