What is known?
- Most deaths of COVID-19 pneumonia are caused by respiratory failure
due to cytokine storms and there is no effective and specific
treatment is not yet.
- Glucocorticosteroids (GCs) are known to functions anti-inflammatory,
anti-allergic, and hypothermic due to reducing levels such cytokines
and chemokines ( IL-8, monocyte chemoattractant protein-1, IL-6,
IFN-γ, and IL-4.)
- The World Health Organization and guidelines suggested low-dose
corticosteroids as adjunctive therapy in hospitalized severe COVID-19
pneumonia.
- Pulmonary fibrosis might be developed in the post-covid period.