What is new?
- High-dose GCs use could not be decreased mortality, however, the time
to give GCs is extremely important that the early high-dose GCs use
was shown to decrease the progression of the disease and improve the
resolution of alterations in the pulmonary structures. Concurrent
administration of high doses of steroids to these patients together
with the increase in ferritin levels on the 1st, 3rd, and 5th days of
hospitalization, and the deepening of lymphopenia, and the prominence
of clinical worsening, supports this information.
- This study investigated whether fibrosis develops in patients with
high-dose steroid therapy. Older age, prolonged hospitalization, lower
saturation at admission, higher d-dimer, and increased recurrent
hospitalizations were identified as the indicator for fibrosis in our
study.
- There is not yet a study for predicting fibrosis in the literature.
Although this study consisted of a small group, it can be a guide for
future studies.