Introduction
Myxoid liposarcoma (MLS) is a translocation-related sarcoma. It has a translocation with FUS-DDIT3 or rarely EWSR1-DDIT3 fusion. Some MLS pathology has round cell areas within the tissue that represent histologic progression to high-grade tumors. Round cells account for more than 5% of total cells and have a high malignant and metastatic potential. Clinically, distant metastases to retroperitoneal, abdominal and bone sites occur in about one-third of MLS patients, but cardiac metastases are very rare. This text reports a case of pericardial metastasis in a patient with MLS originating in the left thigh.