Author contributions
T.Y., Z.S. and Y.L. conceived and designed the study, carried out
experiments, and analyzed and interpreted data. Y.W. and H.Z. provided
human samples and assisted with experiments. Z.L. and Y.L designed and
supervised the study and data analysis. Z.S., D.Z., Y.C. and J.S. wrote
the manuscript, with all authors contributing to writing and providing
feedback.