Figure 6. Counts and frequency distribution of clonotypes. (A).Detection times of each clonotype in TIL samples. X axis indicates the
number of samples having the same clonotype. Y axis indicates the
cumulative number of clonotypes. Clonotypes were determined by the
combination of CDR3 sequence, V gene and J gene. The cumulative number
of shared clonotypes were highlighted in the zoomed subplot. Clonotypes
detected in more than one TIL samples were considered as shared
clonotypes. 1.53% clonotypes were detected in more than one TIL
samples, and 0.01% clonotypes were detected in 4-6 TIL samples.(B). Reads fraction of shared clonotypes is shown as table. The
reads fraction ranges at which these shared clonotypes were represented
in their respective TIL samples were summarized in the left column. The
clonotype number in each category and their corresponding percentage in
total clonotype numbers were shown in the middle and right column,
respectively.