Figure 5. uCDR3 diversity characterization. (A). Unique CDR3
comparison between PBMC and TIL. Paired t test P-value was 0.00133.(B). Unique CDR3 counts in each sample. Mean uCDR3 counts of
PBMC, TIL and total samples were shown in colored dash lines as
indicated. (C). Percentage stacked barplot by sample. Colored
bars indicate uCDR3 in different rank ordered by uCDR3 clone abundance.
For example, red bar shows the total percentage of the Top10 ranked
uCDR3 in each sample. (D). Shannon Entropy comparison between
PBMC and TIL. Paired t test P-value was 0.0004. (E). Shannon
Entropy in each sample. Mean Shannon Entropy of PBMC, TIL, and total
samples were shown in colored dash lines as indicated.