In this report, we present a rare case of severe mitral regurgitation
due to isolated mitral valve chordal rupture without valve leaflet
prolapse in a patient with Fabry cardiomyopathy. This finding could be
due to subvalvular apparatus storage of glycosphingolipids rather than
fibro-elastic deficiency, underlying how close cardiological follow-up
of Fabry patients must be comprehensive and not only focused on left
ventricular hypertrophy and arrhythmias. We feel that our finding could
be of interest for the readership of your Journal.