Statistical analysis
The chi-square test for trend was used to compare the distribution of
the prevalence of various factors at each of the yearly visits. The
Kaplan-Meier method was applied to estimate the probability of asthma
onset, and the log-rank test was used to compare the probability between
AR phenotypes. All reported P values are 2-tailed, with a P value of
<.05 considered to be statistically significant. Statistical
analyses were performed with GraphPad Prism 8 (GraphPad Software; La
Jolla, California) and SPSS (version 26; SPSS; Chicago, Illinois).