Correspondence and page proofs should be sent to:
Yungling Leo Lee, MD, PhD
Institute of Biomedical Sciences, Academia Sinica, 128 Academia Road,
Sec. 2, Taipei 11529, Taiwan
Tel: +886-2-2652-3013
E-mail: leolee@ibms.sinica.edu.tw
Financial disclosure: This work was supported by the National
Health Research Institutes of Taiwan [NHRI-EX110-10718PC and
NHRI-EX109-10606PI].
Conflicts of interest: The authors declare no conflict of
interest.
Author contributions: Dr. Yang-Ching Chen collected the cohort
data, interpreted the data, and wrote the manuscript. Prof. Yen-Tsung
Huang and Prof. Wen-Harn Pan assisted in the critical part of the
statistical analysis, interpreted data, and revised it critically for
crucial intellectual content. Prof. Yungling Lee reviewed the study
design, collected data, interpreted data, supervised the study, and
revised the manuscript critically for valuable intellectual content. All
authors approved the final manuscript as submitted and published and
agree to be accountable for all aspects of the work.
Word count: 250 for abstract; 3000 for text.