Figure 4. Mediation proportions (%) as calculated in the observational and Mendelian Randomization analyses
Footnotes of Figure 4: The proportion of mediation indicates the proportion of indirect mediation effect to total effect from obesity to asthma. Mediation proportion of the observational models were calculated by single-mediator analysis. Mediation proportion of the MR models were calculated according to equations by Burgess et al.Observational models were adjusted by age, sex, parental education, and household environmental tobacco smoking. Definition of abbreviations: BMI=body mass index; FeNO=fractional exhaled nitric oxide; FEV1/FVC = forced expiratory volume in 1 s/forced vital capacity