Estimation of the confidence intervals
We obtained the 95% confidence intervals (CI) for medically- and
non-medically attended respiratory viruses-associated illness using
bootstrap resampling over 1,000 replications for all parameters included
in the calculations [18]. This included (i) the age- and
year-specific ILI or SRI rates in the base provinces (data source 1),
(ii) the provincial prevalence of the risk factors for pneumonia from
the DHS (data source 3), (iii) the provincial proportion of ARI cases
seeking care from the DHS (data source 3), (iv) the age-specific
respiratory viruses detection rate among ILI or SRI cases tested (data
source 1), (v) the estimated AF for each virus and (vi) the estimated
proportion of individuals seeking care from the HUS (data source 2). The
lower and upper limits of the 95% CI were the 2.5thand 97.5th percentiles of the estimated values
obtained from the 1,000 resampled datasets, respectively.