Burden of severe respiratory illness and those associated with respiratory viruses
During 2013-2015, among individuals of any age the estimated mean annual number of SRI episodes was 2,268,125 (rate: 4,196 per 100,000 population) (Table S5) of which 1,051,701 (46.4%; rate: 1,945 per 100,000 population) were medically attended (Table S6). The SRI rates were highest in infants aged <1 year followed by individuals aged ≥65 years (Figure 4 and Table S5). Overall, among patients with SRI rhinovirus had the highest rate (400 per 100,000 population) followed by RSV (247 per 100,000 population) and influenza (130 per 100,000 population) (Figure 2 and Table S5). Among children aged <5 years RSV had the highest rate (2,026 per 100,000 population) followed by rhinovirus (1,638 per 100,000 population) and adenovirus (667 per 100,000 population) (Figure 2 and Table S5). Among individuals aged ≥5 years rhinovirus had the highest rate (253 per 100,000 population) followed by influenza (98 per 100,000 population) and PIV types 1-3 (39 per 100,000 population) (Figure 2 and Table S5). The respiratory viruses-associated SRI rates were highest in infants aged <1 year followed by children aged 1-4 years with the exception of influenza where the second highest rate was among individuals aged ≥65 years (Figure 4 and Table S5) and PIV type 2 where the highest rate was among individuals aged ≥65 years followed by infants aged <1 year (Figure 5 and Table S8). The rates of medically and non-medically attended respiratory viruses-associated SRI are provided in Tables S6, S7 and S9.