Search strategy and study selection:
PubMed (Medline) and Cochrane were searched in depth from the time of
inception of the study to August 1st, 2022. Literature and preprints
were identified through searches of ClinicalTrials.gov, Google Scholar,
and Medrxiv. A search strategy was created using keywords and Medical
Subject Headings (MESH terms) which included [Finerenone OR
Non-steroidal mineralocorticoid receptor antagonist OR Non-steroidal
MRA] AND [ Cardiac outcomes OR Cardio renal outcomes] AND [Type
2 diabetes OR Diabetes Mellitus]. The search methodology is described
in full in the Supplementary Table S1. The search results were returned
without any sort of restriction or filtering. Text written in a language
other than English was translated using Google’s built-in translate
service. To find applicable studies, a manual search of reviews was
carried out. Titles, full texts, and abstracts of studies were screened
by two reviewers (MK and SK) independently. To further eliminate
duplicates, we imported the relevant studies into Endnote X9 (Clarivate
Analytics, US).