Search strategy
EMBASE (1980 to January 2021) and PubMed (1950 to January 2021) were
systematically searched as well as the reference lists of the selected
articles. Initially, a search was conducted for comparative studies
comparing the pregnancy outcomes in the carriers and noncarriers with
RPL. Next, a search was conducted to compare the pregnancy outcomes
after attempting EM with those after performing PGD in the RPL carriers.
‘Recurrent pregnancy loss’ , ‘chromosome abnormalities’, ‘reproductive
outcome’ ,‘parental’ and ‘preimplantation genetic diagnosis’ were used
as keywords in the searches performed by a clinical librarian (JJ.H.).
The appendix shows the search strategies in EMBASE, and adapted for
PubMed, which were used to investigate the pregnancy outcomes between
carriers and noncarriers and after EM or PGD in RPL carriers.