5. Conclusions and outlook
As a new discipline, what people need to understand about combinatorial
biomedicine is “5W1H”, that is, “What combination? When to combine?
Where to combine? Who will combine? Why combination? And how to combine
it?” For example, here is The Book of Health in the new era, the
author’s updated working fruit (Figure 1). In fact, not only social
sciences need to be combined, but also natural sciences need to be
combined even more. In real world, people are intentionally or
unintentionally doing related combinatorial works. Thus, it is time to
propose and establish this novel discipline due to obvious advantages in
screening, diagnosis, treatments, prevention and rehabilitation of both
mNCDs and infectious diseases. And the author’s innovative “TCM Hot
Pot” theory is a classical hallmark of combinatorial biomedicine.
Based on the previous works in the last decades, the author has already
developed and proposed in time a novel discipline – combinatorial
biomedicine. A series of classical examples confirmed that combinatorial
biomedicine has a number of obvious advantages in screening, diagnosis,
treatments, prevention and rehabilitation of both mNCDs (such as
cardiovascular disease, diabetes, cancer, stroke, and neurodegenerative
diseases) and mIDs (such as AIDS, Helicobacter pylori infection, and
COVID-19), and will be helpful in the development of life science,
biology and medicine, in particular the pandemic and post-COVID-19 era.