2. Scientific combination is vital and beneficial
Currently, a new paradigm of self-help traditional Chinese medicine (TCM) prescription was created during the early COVID-19 pandemic (2020), and the novel theory and fresh program of “TCM Hot Pot” consists of “Bark-Flower-Fruit-Grass-Leaf-Nucleolus(seed)-Root” [BFFGLNR] [2]. Due to the characteristic advantages, more easy to learn and use, this discovery has won wide recognition and praise from medical peers. In fact, the innovative “TCM Hot Pot” has become a new milestone in the medical field, and will better serve global health. Moreover, when a combination of “TCM Hot Pot” with “the magic polypill”, it will become all-round prescription, and people will no longer be afraid of the COVID-19 pandemic and SARS-CoV-2 infection. At the same time, based on this new combination, novel treatment programs and agents could be developed for cardiovascular diseases (CVD), such as “Fuya Keli” or “Fuya Decoration” for hypertension, which is relative to Shensong Yangxin Capsule or “Wenxin Keli” for arrhythmia [3,4], “Tongxinluo Capsule” for coronary heart disease [5], and “Qili Qiangxin Capsule” for chronic heart failure [6].
Generally speaking, on the one hand, the TCM prescription itself is composed of several to dozens of herbs, and the names of many famous clinical trials were combined, such as the CAST trial [7], the SPRINT trial [8], and the HOPE-3 trial [9]. On the other hand, many novel technologies and therapies in the biomedical field are also combined, and there are some classical examples in both major non-communicable diseases (mNCDs) including CVD, diabetes, and cancer, and major infectious diseases (mIDs) including Helicobacter pylori (HP), tuberculosis (TB),  human immunodeficiency virus-1 (HIV), and COVID infection. For example, new “four-combined treatment, FCT” or “quadruple treatment” for chronic heart failure, “triple-combination therapy, TCT” for eradicating Hp infection in chronic gastritis and peptic ulcer as well as the famous “cocktail therapy” for AIDS. Therefore, scientific combinations are vital and beneficial to better efficacy in clinical medicine.