Introduction
The prevalence of congenital adrenal hyperplasia is ranging between one in 10,000 to one in 67,000 live birth (1). Studies have reported that individuals with adrenal insufficiency have an increased rate of respiratory infection-related deaths, possibly due to impaired immune function and they are more likely to develop a severe course of the disease as well (2, 3). European Society for Pediatric Endocrinology (ESPE) recommends increasing the hydrocortisone dose, according to the general “sick day rules” in children with congenital adrenal hyperplasia. The suggested oral stress dose for an adult is 20 mg hydrocortisone every 6 hours, if they deteriorate more during acute coronavirus disease 2019 (COVID-19) infection, they advise immediate (self-)injection of 100 mg hydrocortisone intramuscularly, followed by intravenous infusion of 200 mg hydrocortisone per day, or until this can be established, administration of 50 mg hydrocortisone every 6 hours. Also, advise on doses for infants and children (3).
We present a case report of a child with a previous diagnosis of congenital adrenal hyperplasia (CAH) who was found to have SARS-CoV-2 infection.