Statistical analysis
Statistical analyses were performed using SPSS version 17.0 (SPSS,
Chicago, IL) and MedCalc version 11.0.1.0 (MedCalc Software, Mariakerke,
Belgium). A P value<0.05 was considered to indicate statistical
significance. Continuous variables are expressed as mean±standard
deviation (SD) and categorical variables as numbers or percentages. All
data were first analyzed to assess the normality of their distribution
using Kolmogorov-Smirnov tests. Paired sample t tests were used for
comparisons of measurements between 3D ASD models and 2D-TEE images, 3D
ASD models and 3D-TEE images. A Bland-Altman analysis in MedCalc
statistical software was performed for investigate consistency of the
ASD size parameters measured between 3D models and 3D-TEE images, as
well as measurements between 3D models and 2D-TEE images. Correlations
between the size of ASD occluder applied intraoperative and the ASD
parameters measured from 3D printed ASD models were determined by linear
regression analysis. Interobserver and intraobserver agreement were
analyzed by the intraclass correlation coefficient (ICC), a p values
below 0.05 were considered statistical significance.