Clinical characteristics of the study population according to
maternal ESBL-E vaginal colonization
We also compared the maternal baseline characteristics according to
ESBL-E vaginal colonization (Table 3). During the study period, 64
patients (4.4%) were confirmed to be positive for ESBL-E based on the
vaginal culture findings. As shown in Table 3, the rates of IVF-embryo
transfer pregnancy, IIOC, and cerclage before admission were
significantly higher in the ESBL-E-positive group. In addition, the rate
of antibiotic treatment before vaginal culture was significantly higher
in the ESBL-E-positive group than in the ESBL-E-negative group (43.8%
vs 15.0%, P < 0.001). The gestational age at admission
was significantly lower in the ESBL-E-positive group than in the
ESBL-E-negative group. We compared the duration of antibiotic use in 238
patients who used antibiotics before vaginal culture according to ESBL-E
vaginal colonization. The median duration of antibiotic treatment was
significantly longer in the ESBL-E-positive group than in the
ESBL-E-negative group (7.0% vs 4.0%, P = 0.015).