Main Findings
Our study clearly showed a significant increase in the rate of ESBL-E
vaginal colonization, especially ESBL-producing E. coli , in
high-risk pregnancies over the past decade. We also demonstrated that
prior antibiotic treatment and cerclage were the independent risk
factors for ESBL-E vaginal colonization after adjusting for confounding
variables. In addition, maternal ESBL-E vaginal colonization was
associated with earlier gestational age at admission and delivery and
higher rate of EONS, especially in cases of proven sepsis.