Introduction
Laryngeal neuroendocrine carcinomas (LNECs) are rare tumors of the
larynx with a wide spectrum of clinicopathological manifestations.
Generally, laryngeal neuroendocrine neoplasms were divided into 2
categories, epithelial and neural, based on their origin. The epithelial
subgroup consisted of typical carcinoid, atypical carcinoid, small cell
neuroendocrine carcinoma, and large cell neuroendocrine carcinoma. The
neural neuroendocrine neoplasm subgroup is mainly referred to as
paraganglioma. 1
Among these categories, atypical carcinoid is the most common form of
neuroendocrine carcinomas in the larynx .Also; prognosis is getting
worse from typical carcinoid to small cell neuroendocrine carcinoma.2 Laryngeal neuroendocrine neoplasms represent 0.5 to
1% of laryngeal epithelial carcinomas, occurring more frequently in the
supraglottic region with male predominance. 3
In this study, we presented a rare case of poorly differentiated NEC
(small cell) and described its clinicalopathological presentation. The
presentation of this tumor with respiratory distress in a non smoker
male patient with a small size mass in subglottic area is the
interesting feature of this report.