<div>ABSTRACT</div><div><b>Background:</b> The role of intra-operative parathyroid hormone
(IOPTH) monitoring during parathyroidectomy for primary
hyperparathyroidism has long been debated.</div><div><b>Objectives</b> : Our main goal was to investigate the cure rates of
parathyroidectomy for primary hyperparathyroidism with and without IOPTH
monitoring. Our secondary goal was to investigate if operating room time
can be saved when not using IOPTH monitoring.</div><div><b>Design</b> : A retrospective analysis of patients who underwent
parathyroidectomy for PHPT for a single adenoma between 2004-2019 was
performed. Cure rates and operating room time were compared.</div><div><b>Results</b> : 423 patients were included. IOPTH was used in 248
patients (59%). Four patients were not cured, two from each group, with
no significant difference between the groups (<i>98.8%</i> vs. 99.1%,
p=0.725). Surgery time was significantly longer in the IOPTH group,
p&lt;0.001.</div><div><b>Conclusions:</b> There is no advantage for using IOPTH during
parathyroidectomy in suitable clinical setting. A focused procedure may
be safely performed without IOPTH while achieving non-inferior success
rates and reducing operative time.</div>