Introduction
Whereas venous thromboembolism (VTE) is a frequent clinical event in patients with cervical cancer [1], nonbacterial thrombotic endocarditis (NBTE), formerly known as marantic endocarditis, has rarely been described associated to gynecological malignancy [2] and in most of the cases, the diagnosis was confirmed postmortem [3, 4]. NBTE is considered as a manifestation of an overall prothrombotic state [5] characterized by valve associated masses consisting of platelets and fibrin in absence of bacteria and without inflammatory destruction of the heart valves.
We report a case of NBTE of all heart valves and the atrial septum in a patient suffering from clear cell cervical cancer resulting in fatal venous and arterial thromboembolic events.