Introduction
Whereas venous thromboembolism (VTE) is a frequent clinical event in
patients with cervical cancer [1], nonbacterial thrombotic
endocarditis (NBTE), formerly known as marantic endocarditis, has rarely
been described associated to gynecological malignancy [2] and in
most of the cases, the diagnosis was confirmed postmortem [3, 4].
NBTE is considered as a manifestation of an overall prothrombotic state
[5] characterized by valve associated masses consisting of platelets
and fibrin in absence of bacteria and without inflammatory destruction
of the heart valves.
We report a case of NBTE of all heart valves and the atrial septum in a
patient suffering from clear cell cervical cancer resulting in fatal
venous and arterial thromboembolic events.