2.1, Subjects
From June 1 to August 31, 2021, a retrospective observational study was
conducted on 55 infants (male: female = 27: 28, median age=5 months
old), who were admitted to our hospital for respiratory infection caused
by RSV, and underwent a routine breath sound
analysis13, 16). In all patients, the clinical course,
severity of illness and medical history were checked.
The study protocol was approved by the institutional review board of
Tokai University Hospital (IRB number; 21R126, approval date; August 27,
2021), and the opt-outs were conducted at our outpatient clinic (from
August 28 to November 30, 2021). For infants who were finally diagnosed
with RSV-induced acute bronchiolitis, we informed their legal guardians
about the study by letter, and their written informed consent was
obtained.