Nasal outcomes
The postoperative Lund-Kennedy scores, SNOT-22 scores and TIBSIT scores
were summarised in Fig. 2. Postoperative Lund-Kennedy score was
significantly lower in the transseptal group than in the transnasal
group (P < . 001). Post-hoc analysis revealed that the
Lund-Kennedy scores were also lower at every timepoint after surgery
(2.72 vs, 5.08 at 2 weeks, 0.88 vs. 3.52 at 1 month, 0.48 vs. 2.12 at 3
months, 0.04 vs. 1.76 at 6 months, all adjusted P <
. 01). SNOT-22 showed also a lower postoperative scores in the
transseptal group than in the transsnasal group at 6 months after
surgery (4.40 vs. 7.36, P = . 005). Nevertheless, the TIBSIT
scores were not significantly different between the two approaches (41.6
vs. 42.4 preoperatively, P = . 68; 41.6 vs. 40.2 postoperatively,P = . 46). The olfactory status based on normal values of
different gender and age remained unchanged for all patients.
Table 3 showed the effect of transseptal approach on the postoperative
Lund-Kennedy scores and SNOT-22 scores using regression models. The
univariate model revealed a significant lower Lund-Kennedy scores and
SNOT-22 scores in the transseptal group (β, -2.09; 95% confidence
interval (CI), (-2.54, -1.64), P < .001 and β, -2.96;
95% CI, (-4.98, -0.93), P = .005, respectively). After
controlling age, sex, Hardy grade, presence of regional invasion and
endocrine function, transseptal approach remains an independent factor
for lower Lund-Kennedy scores and SNOT-22 scores (β, -2.24; 95% CI,
(-2.73, -1.75), P < .001 and β, -2.46; 95% CI, (-4.60,
-0.93), P = .02, respectively).