Statistical analysis
Student’s t test and Chi-square test/Fisher’s exact test were used for
comparisons of characteristics of the two groups. The sequential changes
in Lund-Kennedy scores were analysed with repeated measures ANOVA,
followed by comparisons between groups at the 4 specified timepoints
using Student’s t test with Bonferroni correction. The effect of
transseptal approach on SNOT-22 scores and Lund-Kennedy scores was
further analysed using linear regression and generalised estimating
equations. A P value less than .05 was considered statistically
significant. All of the analyses were conducted with R, version 4.0.2.