Key points
- The transseptal approach for endoscopic endonasal transsphenoidal
adenomectomy (TSA) is a promising procedure owing to its less injury
to nasal mucosa. However, because limited space may compromise
resection, whether it is a worthy trade-off remains to be validated
and no studies reported simultaneously both rhinological and
neurosurgical outcomes.
- This study revealed that the postoperative SNOT-22 and Lund-Kennedy
endoscopic scores were significantly lower in the transseptal group
than in the transnasal group. The olfactory function test using TIBSIT
revealed no significant difference between the two groups.
- The neurosurgical outcomes, including gross total resection, hormone
control and hospital stay, were similar between the two groups. The
rate of complications were not significantly different between the two
groups.
- After controlling all possible confounding factors, transseptal
approach remained an independent factors of lower SNOT-22 scores and
Lund-Kennedy scores.
- The endoscopic transseptal TSA provides better recovery of nasal
mucosa and intact olfactory function without compromising
neurosurgical outcomes.