Results
The demographic data of the study population was shown in Table 1 and
the maternal baseline characteristics were similar in both groups
(p>0,05). In table 2, the clinical points of SARS-CoV-2
infection were shown and the gestational age of the SARS-CoV-2 infection
diagnosis was 20 (8–34). In the RSI group, 18 (37.5%) patient had mild
disease, 20 (41.6%) patient had moderate disease, and 10 (20.8%)
patient had severe disease. There was no critical patient in this group.
Thirty (62,5%) of the study patients were hospitalized and 10 (20,8%)
of them needed respiratory support. The echocardiographic findings were
given in Table 3. All fetuses had normal cardiac morphology. The median
value of ultrasound evaluation was 34 (2.6) weeks of gestation in the
RSI group, and 32 (7.6) weeks in the control group (p=0.565). LCO z
score was found significantly lower in the RSI group than the control
group (p=0,041). Table 4 shows the relation between SARS-CoV-2 infection
severity and fetal echocardiographic findings. LCO and CCO z scores were
significantly lower in the severe disease group than mild disease,
moderate disease, and control groups (p=0,019 and p=0,013). CCO
(mL/min/kg) was found to be decreased in the severe disease group than
mild disease and control groups (p=0,044). Perinatal outcomes were given
in Table 5. Gestational age at birth and birth weight were significantly
lower in the severe disease group compared to mild disease, moderate
disease, and control groups (p<0,001 and p=0,020). Fetal
distress, preterm delivery rate, and neonatal intensive care unit (NICU)
admission were higher in the severe disease group than controls
(p=0,010, p=0,009, and p<0,001 respectively).