b. Fungal serology: anti-fungal specific IgG
Since fungi are ubiquitous, detecting anti-fungal specific IgG in the
blood of individuals free of fungal disease is common. In contrast to
specific IgE, IgG concentrations in healthy individuals vary greatly
depending on the antigen, therefore reference values have to be
established for each antigen (111). High concentrations of anti-fungal
specific IgG may support ABPA/ABPM, HSP, infectious aspergillosis.
Unmet needs
The diversity and abundance of the fungal exposome stands in contrast
with the unmet needs in knowledge and methods related to fungal effects
on human health.