V.2.3. Hematology
Systemic or local eosinophilia is a hallmark of fungal allergic diseases (100). Eosinophils are readily counted and interpreted through a basic white blood cell count. Blood eosinophilia, often defined as > 500 elements/mm3 but sometimes at lower levels, e.g. 150 elements/mm3 (101), is an inconsistent marker of a predominantly type 2 response and atopic orientation, without specificity for ongoing fungal-related atopic disease. It is subject to variations related to comorbidities and ongoing treatments, especially corticosteroids (102).