Patient characteristics
ICU patients (n=31) Non-ICU patients (n=39)
p
Age, years 59 (48-65) 56 (48-61) 0.40
Male gender, n (%) 26 (84) 24 (62) 0.04
BMI, kg/m2 31 (29-35) 30 (25-34) 0.20
Smoking Status, n (%)
None
14 (45)
27 (69)
Active Smoker
0 (0)
2 (5)
Former Smoker
17 (55)
10 (26)
Smoking time, years 30 (10-40) 15 (13-25) 0.25
Comorbidities, n (%)
COPD
5 (16)
2 (5)
0.13 0.07 0.15 0.46 0.86 0.11
Hypertension
16 (52)
12 (31)
DM
13 (42)
10 (26)
CAD
3 (10)
2 (5)
CHF
1 (3)
1 (2)
Malignancy
0 (0)
3 (8)
Charlson Comorbidity Index 1 (1-2) 1 (1-2) 0.16
Disease Severity
1- No O2 Therapy
0 (0)
18 (46)
<0.001
2- Only O2 Therapy
3 (10)
21 (54)
3- NIV or HFNC
23 (74)
0 (0)
4- IMV
5 (16)
0 (0)
APACHE-2 Score 11 (8-15) -
Treatment, n (%)
Hydroxychloroquine
21 (68)
33 (85)
0.09 <0.001 <0.001 <0.001 0.009 0.2
Favipravir
31 (100)
19 (49)
Corticosteroid
26 (83)
3 (8)
Convalescent plasma
12 (39)
0 (0)
Tocilizumab
5 (16)
0 (0)
Antibiotics
31 (100)
37 (95)
Complications, n (%)
Acute renal failure
4 (13)
2 (5)
0.39 0.045 0.26
Hepatotoxicity
9 (29)
4 (10)
Sepsis
1 (3)
0 (0)
Length of hospital stay, days 19 (14-28) 8 (6-11) <0.001
Length of ICU stay, days 9 (6-15) -
Time from symptoms to follow up, days 209 (189-219) 190 (186-209) 0.016