Temporal and Geographical Distribution Analysis.
A total of 683 Chinese CPV-2 records were retrieved from Genbank and
related publications. The details were presented in Supporting
Information. Additionally, 23 strains (collected from 2018 to 2019) in
this study were included.
The temporal distribution analysis was given in Figure 3. The detection
rate of New CPV-2a has declined since 2016, and New CPV-2b showed the
same tendency. In contrast, CPV-2c has been consistently growing since
2014, thereby replacing New CPV-2a as the predominant variant in China
after 2018.
Figure
3 Temporal Distribution of CPV-2 in China from 2014-2019.
Considering the dynamic change of the genotype of Chinese CPV-2 strains
in recent years, the geographical distribution analysis was divided into
two periods. The former was from 2014 to 2016, and the latter was from
2017 to 2019. Their respective data was given in Figure 4.