Discussion:
The present study was carried out to assess the prescribing pattern of antibiotics in a tertiary care hospital using WHO core indicators. Generic prescribing of drugs was relatively minor and mainly not prescribed from EDL. Our investigation recommends that procedures to control silly utilization of antibiotics should be executed and the rules utilized for treatment of patients should be redesigned intermittently.
Irrational prescribing of antibiotics is a general medical issue, prompting to antibiotic resistance. Understanding the prescribing pattern of antibiotics is pivotal to handling irrational prescription. Formulation of an arrangement for hospital antibiotic use and an instructive program particularly for junior specialists is necessary. Rules for antibiotic practice in the public and confining the level of health care practitioners who can prescribe antibiotics are compulsory.
Data about antibiotic use designs is fundamental for a valuable way to deal with issues that emerge from the various antibiotics available.
The results of our study were slightly similar to 18in which the average number of drugs per encounter was 6.11, while the percentage of drugs prescribed by generic names were 69.81%, the percentage of antibiotics prescribed was 50.10%, while the percentage of injections prescribed was 72.70% and about ninety four percent (94%) of drugs were prescribed from EDL.
The results of our study were comparable to 11 in which the percentage of male was 204 (66.6%) and percentage of females was 102 (33.3%). The total drug prescribed was 1749 while the average drugs per patients were 5.7. The percentage of the drugs prescribed in their generic names was 18%. The percentages of prescriptions which had one or more antibiotics prescribed were 128 (41.8%) and the percentage of prescription which had at least one injection was 138 (45.1%) and percentage of prescription in which the drugs were prescribed from the NEDL were (35%).
The result of our study was similar to 4 in which the most commonly antibiotic combination utilized was Amoxicillin and Clavulanic acid & Cefotaxime and Sulbactam.
The results of our study was slightly comparable with the results of13 in which the usually prescribed antibiotic were cloxacillin (13.4%), amoxicillin (16.4%), chloramphenicol (11.6%), ceftriaxone (9.8%), ampicillin (15%), gentamicin (14.9%) and penicillin (12.4%).
On the base of our study the prescribing pattern used at this Hospital for use of antibiotics, use of injections, generic concept and prescribing drugs from EDL shows deviation from the standards guidelines of WHO. On the other hand, poly-pharmacy was found to be a problem in our study. So the responsibility of the doctors is to develop prescribing patterns which will support to reduce the intensity of the drugs related problem. Teaching hospitals have responsibility to promote rational prescribing by their staff and the future generations of doctors.
This issue might be decreased by building up an ASP, presenting the practice of antibiotics with the help of culture and sensitivity tests, and creating institutional rules. Consequently, this investigation gives proof to the need and a path forward for the foundation of an ASP in the hospital.