Discussion:
The present study was carried out to assess the prescribing pattern of
antibiotics in a tertiary care hospital using WHO core indicators.
Generic prescribing of drugs was relatively minor and mainly not
prescribed from EDL. Our investigation recommends that procedures to
control silly utilization of antibiotics should be executed and the
rules utilized for treatment of patients should be redesigned
intermittently.
Irrational prescribing of antibiotics is a general medical issue,
prompting to antibiotic resistance. Understanding the prescribing
pattern of antibiotics is pivotal to handling irrational prescription.
Formulation of an arrangement for hospital antibiotic use and an
instructive program particularly for junior specialists is necessary.
Rules for antibiotic practice in the public and confining the level of
health care practitioners who can prescribe antibiotics are compulsory.
Data about antibiotic use designs is fundamental for a valuable way to
deal with issues that emerge from the various antibiotics available.
The results of our study were slightly similar to 18in which the average number of drugs per encounter was 6.11, while the
percentage of drugs prescribed by generic names were 69.81%, the
percentage of antibiotics prescribed was 50.10%, while the percentage
of injections prescribed was 72.70% and about ninety four percent
(94%) of drugs were prescribed from EDL.
The results of our study were comparable to 11 in
which the percentage of male was 204 (66.6%) and percentage of females
was 102 (33.3%). The total drug prescribed was 1749 while the average
drugs per patients were 5.7. The percentage of the drugs prescribed in
their generic names was 18%. The percentages of prescriptions which had
one or more antibiotics prescribed were 128 (41.8%) and the percentage
of prescription which had at least one injection was 138 (45.1%) and
percentage of prescription in which the drugs were prescribed from the
NEDL were (35%).
The result of our study was similar to 4 in which the
most commonly antibiotic combination utilized was Amoxicillin and
Clavulanic acid & Cefotaxime and Sulbactam.
The results of our study was slightly comparable with the results of13 in which the usually prescribed antibiotic were
cloxacillin (13.4%), amoxicillin (16.4%), chloramphenicol (11.6%),
ceftriaxone (9.8%), ampicillin (15%), gentamicin (14.9%) and
penicillin (12.4%).
On the base of our study the prescribing pattern used at this Hospital
for use of antibiotics, use of injections, generic concept and
prescribing drugs from EDL shows deviation from the standards guidelines
of WHO. On the other hand, poly-pharmacy was found to be a problem in
our study. So the responsibility of the doctors is to develop
prescribing patterns which will support to reduce the intensity of the
drugs related problem. Teaching hospitals have responsibility to promote
rational prescribing by their staff and the future generations of
doctors.
This issue might be decreased by building up an ASP, presenting the
practice of antibiotics with the help of culture and sensitivity tests,
and creating institutional rules. Consequently, this investigation gives
proof to the need and a path forward for the foundation of an ASP in the
hospital.