4. Epidemiology of CQV (Origin and Transmission):
CQV was first isolated in 2004 from mosquitoes and reported during the surveillance of arboviruses in acute pediatric encephalitis cases in Vietnam (Bryant et al., 2005) and late in Uganda (Mossel et al., 2017). Viruses of family Peribunyaviridae infect the vertebrates and reside in a zoonotic infection cycle that spreads across livestock and human beings through an arthropod intermediate (Saeed et al., 2001). Globally, arboviruses (arthropod-borne viruses) have turned into a major public health concern with the emergence and re-emergence of arboviral diseases. Most of the arboviruses act as a zoonotic spillover from an infected reservoir hosts (dogs, mosquitoes, birds, and ruminants) to humans (accidental host) (Go et al., 2014; Bodewes and Kuiken, 2018), i.e.,the spread of a pathogen from an infected vertebrate to a human is caused by mosquito bite (Figure-2) (Whitmer et al., 2018).