Email of the authors:
Balasubramanian Ganesh (BG): niedrbganesh@gmail.com
Thangarasu Rajakumar (TR): rajkumar18388@gmail.com
Sridharan Vasumathy (SV):vasumathysridharan@gmail.com
Sridharan Sowmya (SS):sowmyasrithar@gmail.com
Natesan Manikandan (NM): maninatesan87@gmail.com
Harpreet Kaur (HK): kaurh.hq@icmr.gov.in
Abstract: (293 words)
The world is now experiencing the catastrophe of global pandemic ’COVID-19’, most serious public health crises in this century. Recently, another virus named “Cat Que Virus” (CQV) seems to be causing its terrible repercussions in the worlds’ largest populous country ‘China’, the origin of SARS-CoV during 2002-2003, and the current pandemic SARS-CoV-2 since December 2019. Recently, the presence of IgG antibody among two persons in the state of Karnataka for CQV was reported in India, the worlds’ second-largest populous country. This means the virus is in circulation in the sub-continent. The presence of the vector mosquitoes (Aedes species, Culex species) and the ambient climatic conditions suitable for vector breeding in the country needs to be taken into account while planning to implement holistic strategies appropriate for control and preventive measures. “One Health approach” is the topmost option covering humans, animals/vectors and the environment to curb the spread/transmission of infectious diseases in general. It is also necessary to study the transmission dynamics and pattern of this emerging virus, its life cycle, the natural reservoir of the virus, the intermediate host and the accidental host with respect South-East Asia, so that necessary remedial action can be planned well before an epidemic. At present, the outbreak of CQV is certainly a warning to the general population around the world. Considering the global imminent health threats posed by CQV, there is an urgent need for active surveillance, monitoring, effective vaccination, and a standard treatment modality of this disease. Given the epidemiological aspect of CQV, control and prevention measures are essential to stop the spread of the virus. At present, there is no information available on CQV; however, this current review article has covered the required data, which will be helpful to control the spread of the CQV.
Keywords: Cat Que Virus; Orthobunyaviruses ; Vector-borne infection; Tropical nations; Public health; Global threat;
1. Introduction: (1875 words)
The world is now facing one of the most destructive pandemics ever recorded. Panic of death due to Corona Virus Disease-2019 (COVID-19) is all around the world and under the influence of this outbreak, another dangerous virus called Cat Que Virus (CQV) appears to have had its dreadful consequences in China. CQV was first identified from the mosquitoes of Cat Que Commune, Hoai Duc District of Ha Tay Province in Northern Vietnam during the improved surveillance activities for Japanese Encephalitis Virus (JEV), as well as surveys for arbovirus activity in regions where Acute Encephalitis Syndrome (AES) cases had occurred during the period of 2004 causing morbidity and mortality among children due to acute febrile illness and non-JEV AES. Several people in the world have been reported infected so far, and this outbreak is gradually beginning to spread in India as well.The findings of the recent study conducted by the ICMR-National Institute of Virology (NIV), Punereported that 2 out of 883 human serum samples had anti-CQV IgG antibodies. This indicates that these two individuals have been infected by the virus at some point in time. In specific, CQV spreads through pigs and species of mosquitoes known asAedesandCulex (Ae. aegypti, Cx. quinquefasciatus, and Cx. tritaeniorhynchus ).Both of these life forms exist in India and are vulnerable to CQV. CQV can cause diseases such as meningitis, acute febrile illness, and pediatric encephalitis to humans (Shete et al., 2020).