Figure 1: Fasting plasma glucose levels at 2 and 16 weeks of treatment. D+A; diabetic mice treated with Vitamin A. *P<0.05 compared to control nondiabetic mice.
Fasting blood insulin levels were examined at week 2 and week 16 post-injection. Elevated blood insulin levels (9.3 ± 7.1 mM) were observed at the third day post-injection. At two weeks both untreated and treated diabetic mice showed a significant increase in fasting insulin levels (9.8 ± 8.7 mM, 9.7 ± 7.5 mM,P  < 0.05, respectively) compared with that of normal mice. At 16 weeks both untreated and treated diabetic mice still showed a significant increase in their fasting insulin levels (9.7 mM ± 7.7, 8.9± 8.3 mM, P  < 0.05, respectively) compared with that of normal mice (Figure 2).