Figure 4: HDL levels at 2 weeks and 16 weeks of treatment. D+A;
diabetic mice treated with Vitamin A *P<0.05 compared
to control nondiabetic mice, **P<0.05 compared to
diabetic mice.
Total cholesterol was examined at week 2 and week 16 post-injection. At
two weeks both untreated and treated diabetic mice showed a significant
increase in their total cholesterol levels (5.8 ± 2.9 mmol/l, 5.9
± 2.4 mmol/l, P < 0.05, respectively) compared with
that of normal mice. At 16 week treated diabetic mice showed a
significant decrease in their total cholesterol levels (1.9 ± 0.9
mmol/l, P < 0.05) compared with that of untreated
mice (Figure 5).