Figure 2: Fasting plasma insulin levels at 2 and 16 weeks of treatment. D+A; diabetic mice treated with Vitamin A. *P<0.05 compared to control nondiabetic mice
LDL levels were examined at week 2 and week 16 post-injection. At two weeks both untreated and treated diabetic mice showed a significant increase in their LDL levels (589 ± 27.9 mg/dl, 566 ± 24.4 mg/dl, P  < 0.05, respectively) compared with that of normal mice. At 16 weeks treated diabetic mice showed a significant decrease in their LDL levels (369 ± 32.9 mg/dl, P  < 0.05) compared with that of untreated mice (Figure 3).