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\begin{document}

\title{Current approaches in the therapeutic use of herbal medications for
chronic kidney diseases}



\author[1]{Pranjali  Borkar}%
\author[1]{Vaishali  Yadav}%
\author[1]{Rajnarayan Tiwari}%
\author[1]{Ravindra Samarth}%
\affil[1]{ICMR-National Institute for Research in Environmental Health}%


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  \date{May 26, 2024}


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\begin{abstract}
A combination of herbal medication and pharma-therapies is usual
practice to treat chronic kidney disease especially in Asian region.
Because of limited treatment options for chronic kidney disease (CKD),
the use of traditional herbal medication to alleviate the urogenital
problems is the alternate therapeutic selection. Only few studies are
available in supporting the usefulness of medicinal plants for CKD,
though people are using it since very long. Many active ingredients of
traditional medicinal plants are unidentified which eventually results
into undetermined toxicities. Here, we made attempt to summarize the
recent outcomes for the use of herbal medicine in treatment of CKD in
human and in animal studies. About 51 studies were found to describe the
utilization of herbal drugs in treatment of CKD in both human and
laboratory animals, 19 studies described the clinical application of
about 14 medicinal plants used against CKD in human and 32 studies
demonstrated the beneficial use of 19 medicinal plants in animal models
and in vitro studies for CKD treatment. To embody the therapeutic use of
herbal medications in CKD, molecular studies need to execute to identify
active components of medicinal herbs and their mechanism of action. A
well-designed clinical trials and rigorous pharmacological studies are
warranted for determination of the safety standards required for
therapeutic agents of herbal medicines.%
\end{abstract}%



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\verb`Edited Manuscript Final.doc`  available at \url{https://authorea.com/users/470222/articles/562518-current-approaches-in-the-therapeutic-use-of-herbal-medications-for-chronic-kidney-diseases}

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