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\begin{document}

\title{Therapeutic interventions in the~treatment of SARS-CoV-2: A review}



\author[1]{Bhavdeep Sharma}%
\author[1]{Anushree Pant}%
\author[1]{M Vasundhara}%
\affil[1]{Thapar Institute of Engineering and Technology}%


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  \date{May 25, 2024}


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\begin{abstract}
SARS-CoV-2 has emerged as a life-threatening virus claiming number of
lives and adversely affecting the physical, mental health and economic
growth world-wide. There is an urgent need to treat this life
threatening condition as it is adversely affecting the mankind. Because
of the pandemic, the global economic rate has declined by several folds.
Initially, FDA approved drugs for other diseases have been repurposed
for treatment, but these therapeutic strategies do not provide targeted
treatment to treat Covid-19. Broad spectrum antiviral drugs, their
combinations and life supporting systems provide effective result to
inhibit viral entry and replication. Other therapeutic options like
Angiotensin converting enzyme-2 (ACE2) blockers and Transmembrane
protease, serine 2 (TMPRSS2) inhibitors and plasma therapy have proven
to have greater potential to target the virus. In this review, we have
discussed a number of therapeutic interventions like use of antiviral
drugs, drug combination therapy and other therapeutics that are
currently exhibiting effective results and helping to lower the
mortality rate significantly. Vaccine is the best option as it elicits
immune response and provides long-term immunity to fight against such
infections. This review also focuses on the current vaccine development
scenario practiced worldwide.%
\end{abstract}%



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\verb`Covid-19 review.docx`  available at \url{https://authorea.com/users/470569/articles/562633-therapeutic-interventions-in-the-treatment-of-sars-cov-2-a-review}

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