Introduction
Salmonella enterica includes more than 2500 serovars and
represents a major food-borne pathogen, which mainly causes
gastroenteritis. However, focal suppurative infections of almost any
organ may occur and produced different characteristic clinical syndromes
(Lombardi et al., 2014; Galanakis et al., 2007). Meningitis is diagnosed
in less than 1% of clinical salmonellosis; Salmonella infections
account for 0.8% of all cases of osteomyelitis. Salmonellainfection also causes abscesses, including intra-abdominal infections,
spontaneous peritonitis, splenic abscess, and knee joint infections
(Ispahani et al., 2000). Many non-typhoid Salmonella serotypes,
including S. Enteritidis, S. Typhi, S. Typhimurium,S. Newport, S. Choleraesuis, S. OhiO, and S.Virchow, have been reported to be the causing factor in osteomyelitis or
septic arthritis in humans (Salem, 2014; McAnearney et al., 2015; Kato
et al., 2012; Weston et al., 2015; Katsoulis et al., 2004; Sy et al.,
2013; Morgan et al., 1990). S. Virchow has also been connected
with meningitis in adults (Lombardi et al., 2014). In this study, the
first Chinese case of infection in the knee joint by S. Virchow
monophasic variant (Salmonella 6,7,14 :r:-) is reported;
this novel serovariant without the fljAB operon was identified by
whole-genome sequencing analysis.