Gestational weight gain ranges and maternal-infant adverse outcomes
among Chinese women with gestation diabetes: a retrospective study
- Qing-Xiang Zheng,
- Xiumin Jiang,
- Yan Lin,
- Gui-Hua Liu,
- Mian Pan,
- Li Ge,
- Xiao-Qian Chen,
- Jing-Lin Wu,
- Xiao-Yun Zhang,
- Yu-Qing Pan,
- Hong HE
Xiao-Qian Chen
Fujian Maternity and Child Health Hospital
Author ProfileXiao-Yun Zhang
Fujian Maternity and Child Health Hospital
Author ProfileAbstract
Objective To identify the ranges of gestational weight gain for Chinese
women with gestational diabetes based on the different pre-pregnancy
body mass index group, and to investigate the association between
gestational weight gain and maternal-infant adverse outcomes. Design A
single-center retrospective cohort study. Setting A tertiary public
women's and children's hospital in China. Population Women with
gestational diabetes. Methods Retrospective analysis of 17,216 women
with gestational diabetes who delivered singleton, registered between
2013 and 2018. Main outcome measures Gestational weight gain ranges,
maternal-infant adverse outcomes. Results A total of 14,517 women were
included finally. In comparison to the recommended gestational weight
gain ranges by the National Academy of Medicine, the Chinese women with
gestational diabetes in this study had a wider weight gain ranges, and
faster rate of gestational weight gain. The risk of adverse outcomes
increased steadily with gestational weight gain in the four body mass
index groups. The ranges of gestational weight gain that were associated
with lower risks of maternal-infant adverse outcomes were 15-20kg,
14-18kg, 4-8kg, and 0-4kg for the underweight, normal weight, overweight
and obese groups, respectively. Conclusions The findings from this study
can be used as a guideline for Chinese women with gestational diabetes.
Healthcare professionals should provide targeted advice to women based
on their pre-pregnancy body mass index to reduce the risks of
maternal-infant adverse outcomes. Future high-quality and multi-center
prospective studies are needed to validate our findings. Keywords
Gestational weight gain, body mass index, gestational diabetes mellitus,
maternal-infant adverse outcomes