Severe SARS-CoV-2 infections in pediatrics are rare and usually
presented as multisystem inflammatory syndrome in children. There are
few descriptions about pediatric oncology patients. We describe a case
of 5-year-old male with acute myeloid leukemia. He presented febrile
neutropenia with skin lesions and progressive clinical worsening. He had
positive RT-PCR test for SARS-CoV-2 and criteria for MIS-C. He received
methylprednisolone, immunoglobulin and granulocyte-colony-stimulating
factor. Anti-interleukin 6 was administrated due to severe lung disease
and refractory to treatment, presenting response and slow clinical
recovery. Chemotherapy was restarted, he didn't present relapse during
treatment and has no sequelae of COVID-19.