Locoregional therapy for cervical lesions
As mentioned previously, none of the drug-based locoregional therapies
so far developed for HPV infection are licensed for the management of
cervical dysplasia. There have, however, been some promising results
from trials of locoregional therapy for cervical lesions. We will now
discuss in greater detail some of these studies involving
5-Flourouracil, Cidofovir and more recently, Lopimune, including some of
the advantages, limitations, and the potential for clinical use of the
various therapies.