Inclusion and Exclusion Criteria
We searched for Randomized Controlled Trials (RCTs), Cohort and
Case-Control studies comparing the serum levels of adiponectin, insulin,
and glucose, as well as the Homeostatic Model Assessment for Insulin
Resistance (HOMA-IR) before and after systematic treatment with
isotretinoin in patients with acne vulgaris. We included only studies
with a published full text in English.