Definitions
Acne vulgaris (AV) is a chronic multifactorial inflammatory disease of the pilosebaceous units of the skin 1. Insulin resistance is defined clinically as the inability of a known quantity of exogenous or endogenous insulin to increase glucose uptake and utilization in an individual as much as it does in a normal population12. HOMA-IR is a quantitative assessment of the contributions of insulin resistance and deficient r-cell function to the fasting hyperglycemia, through the comparison of a patient’s fasting values with the model’s predictions 13.