Definitions
Acne vulgaris (AV) is a chronic multifactorial inflammatory disease of
the pilosebaceous units of the skin 1. Insulin
resistance is defined clinically as the inability of a known quantity of
exogenous or endogenous insulin to increase glucose uptake and
utilization in an individual as much as it does in a normal population12. HOMA-IR is a quantitative assessment of the
contributions of insulin resistance and deficient r-cell function to the
fasting hyperglycemia, through the comparison of a patient’s fasting
values with the model’s predictions 13.