Figure Legend
Figure 1. Flowchart of patient sample identification
Table 1. Baseline (pre-May 2016) clinical characteristics of 29
patients with sickle cell CNS vasculopathy
Figure 2. Example patient images
Axial 3D time of flight (TOF) MRA head and corresponding maximum
intensity projection (MIP) images before (A, B) and after (C, D) the
protocol change.
Before - Images A and B taken with a higher echo time show focal
diminished flow related signal in the right greater than left internal
carotid artery supraclinoid segment (outlined grey arrow and arrowhead).
After - Images C and D taken with a lower echo time show vessel patency
after protocol change (white arrow and white arrowhead).
Figure 3. Example patient images
Axial 3D time of flight (TOF) MRA head and corresponding maximum
intensity projection (MIP) images before (A, B) and after (C, D) the
protocol change.
Before - Images A and B taken with a higher echo time show focal
diminished flow related signal in the A1 segment of the left anterior
cerebral artery (outlined grey arrow and arrowhead).
After - Images C and D taken with a lower echo time show vessel patency
after protocol change (white arrow and white arrowhead).
Figure 4. Treatment plans for 29 patients with sickle cell CNS
vasculopathy pre and post
implementation of a standardized MRA scanning protocol