4. Results:
The study population comprised of 102 neonates; mean age 1.5±0.8 days (Min:1 day, Max:5 days), 65 (63.7%) were age 1 day old at time of echo and 59 (57.8%) neonates were males. Atrial septal defect vs. patent foramen ovale were found in 67 neonates (65.7%) (Table 1).
Averaged GLS (%) was -19.9 ± 1.2 while GLS-derived ejection fraction (%) was 60.0 ± 2.7(Table 2).
Fractional shortening (%) was 34± 3. EF using Biplane Simpsons method (%) 61.0 ± 3,
A Pearson correlation was used to determine the relationship between LV EF by biplane Simpson’s method and Left Ventricle EF by strain. There is a small positive correlation between the LV EF by biplane and LV EF by strain which was statistically significant (r  = 0.294, n  = 102, p =0.003). On the other hand, there is a small negative correlation between the FS and LV EF by strain which shows inconclusive evidence about the significance of the association between the variables (r  = -0.142, n  = 102, p =0.). Apical 4-chamber strain and 4-chamber strain-derived EF was significantly correlated with GLS and GLS-derived EF (r  = 0.756 , n  =102, p<0.001) and (r = 0.735 , n = 102, p<0.001.) respectively . Additionally, there is weak but statistically significant correlation between 4-ch strain-derived EF and biplane Simpson EF (r = 0.204 , n = 102, p=0.039) (Table 3). Comparison of demographic data and echo variables showed no significant difference between male and female (Table 4). By using linear regression analysis, there was a small positive correlation between average EF by biplane method and EF by strain, which was statistically significant (R2  = 0.087, p =0.003) (Figure 3)