Search strategy and date extraction
We searched for randomised controlled trials in the review, involving
adult patients with plaque psoriasis of trunk and limbs. Only studies
that included data from the most recent or comprehensive studies were
included under multiple articles involving the same population and we
investigated the efficacy, safety and tolerability of topical therapies
compared with placebo for patients with plaque psoriasis,in particular
some new drugs.An electronic search of the published literature using
PubMed, Cochrane Library and Embase
databases was conducted by two
researchers independently who searched for publications on topical durgs
in the treatment of plaque psoriasis and published between 01
January 2010 and 20 February 2022.
References within the reviews literature on topical treatment of
psoriasis and selected articles were reviewed to avoid missing relevant
articles.The following information was extracted from the included first
author’s name,publishing date,clinical trial registration number,study
country,blind evaluation,the number of participants, baseline patient
characteristics (age, gender, PASI), treatment regimen, outcome
assessment, and follow-up time.