INCLUSION CRITERIA:
The definition of MIS-N from CDC criteria was used along with published definitions to define neonatal COVID infection, [21, 22] and agreed upon certain inclusion criteria. Once common neonatal conditions mimicking multi- system presentations (E.g., sepsis, birth asphyxia, pneumonia, other common condition) were ruled out by the neonatologist, MIS-N was considered in neonates meeting the following criteria
1. Symptoms presenting from birth to the first four weeks of life.
2. Fever along with two or more systems involvement (fever, if present, is suggestive but not mandatory for diagnosis in the newborn).
3. Evidence of raised inflammatory markers such as CRP, D Dimer, and Ferritin.
4. Evidence of SARS-CoV-2 antibodies in the neonate (considered mandatory for a diagnosis of MIS) and SARS-CoV-2 antigen to be negative during the presentation to rule out active SARS-CoV-2 infection to support the immunological process.