3.5.3 The time to first postoperative analgesic requirement
A total of 14 studies involved 13 interventions reported the time to
first postoperative analgesic requirement (Appendix4 Figure
4.3.1 ). Compared with placebo, flurbiprofen plus dexmedetomidine
(MD=43.05, 95% CI: 28.49, 57.60), adenosine (MD=26.90, 95% CI:11.98,
41.82), magnesium sulphate (MD=23.29, 95% CI:12.27, 34.30) and
dexmedetomidine (MD=11.39, 95% CI:0.93, 21.84) mean longer time to
require first postoperative analgesic (Appendix5 Figure 5.3.2). The
league table (Appendix4 Figure 4.3.3 ) illustrates the results
of each intervention compared to each other. In the ranking probability
plot (Appendix4 Figure 4.3.4 ), flurbiprofen plus
dexmedetomidine was ranked highest among 13 interventions whose SUCRA
values was 98.5.