3.5.2 Cumulative morphine consumption over the 24h
A total of 14 studies involved 11 interventions reported cumulative morphine consumption over the 24h (Appendix4 Figure 4.2.1 ). Compared with placebo, flurbiprofen (SMD= -17.36, 95% CI: -22.13, -12.59) and dexmedetomidine (SMD= -11.83, 95% CI: -17.77, -5.90) mean more morphine consumption at 24h after surgery (Appendix4 Figure 4.2.2 ). The league table (Appendix4 Figure 4.2.3 ) illustrates the results of each intervention compared to each other. In the ranking probability plot (Appendix4 Figure 4.2.4 ), flurbiprofen plus dexmedetomidine was ranked highest among 11 interventions whose SUCRA values was 100.