2.3 OPIOID CONSUMPTION
Medical records were reviewed to determine the type and amount of opioid
administered during two inpatient admissions for anti-GD2 mAb infusion.
Anti-GD2 mAb was infused during two inpatient admissions for induction
chemotherapy as follows:
Course 1: Daily for 4 days (days 2 through 5 of induction chemotherapy)
Course 2: Daily for 4 days (days 22 through 25 of induction
chemotherapy)
During the 8 days (two distinct four-day infusions), patients received
an opioid infusion and bolus doses (morphine, hydromorphone, or
fentanyl) as PCA. Opioid consumption was quantified in morphine
equivalent doses (mg/kg) and summated for the two 4-day time intervals,
respectively.