Blood pressure (BP)
Peripheral blood pressure in offspring exposed to ACS was assessed in eighteen studies 17 1819 20 2122 23 2425 26 2728 29 3031 32 3334. Three of the eighteen studies also assessed central blood pressure 29 3132. The findings of these studies are shown in Table 3. Twelve studies found no difference in blood pressure (peripheral or central, systolic or diastolic) between offspring exposed to ACS and controls. Six studies showed an increase in mean arterial pressure (MAP) in offspring exposed to ACS compared to controls 1719 22 2830 31. These studies were all performed in the early neonatal period, and they reported that an increase in the MAP of the infant which the authors either reported was either clinically beneficial (reducing the need for vasopressor BP support) or the authors reported was clinically irrelevant (a small change which did not persist).