Diagnostic tests
In the LATER 2 study, participating survivors were invited for a number of diagnostic tests, the extent of which was based on age, sex, prior treatment, and participating center. In total, a maximum of seven (functional) tests targeting different health outcomes / organ systems were performed, including dual-energy x-ray absorptiometry (DXA) scan, echocardiogram, electrocardiogram, 6-minutes walking test, hand grip test, pulmonary function test, and 24-hour blood pressure. Some siblings were invited to undergo echocardiogram and electrocardiogram.