Physical stability results: properties at t=0 days Ointment Emulsion Gel Liposomes
pH 7.0 6.0 6.0 7.5
Uniformity Level 2 Level 3 Level 3 Level 3
Extensibility Level 1 Level 2 Level 3 Level 3
Absence of crystals Level 3 Level 3 Level 1 Level 3
Absence of phase separations Level 3 Level 1 Level 3 Level 3
Mean particle size, PdI NA NA NA 178.9 nm, PdI 0.093
Zeta potential (mV) ± SD NA NA NA -41.1 ± 13.4
EE% ± SD NA NA NA 89.19± 4.57
Microbiological stability results: culture samples at t=28 and 56 days Negatives Negatives Negatives Negatives