Table 4 Effect of high and low proBNP in Group A: participants with normal EF
Univariate Logistic Regression Univariate Logistic Regression Univariate Logistic Regression Multiple Binary Logistic Regression Multiple Binary Logistic Regression
Cases Positive/negative 72/1688
Group n p-value HR p-value HR (CI)
PACS (%) 72/1710 0.430
ACS (%) 72/1710 0.007 1.032 (1.009-1058) n.s.
ATS (%) 72/1710 0.010 0.977 (0.959-0.994) 0.031 0.978 (0.958-0.998)
Atrial SR S (1/s) 72/1710 0.090 0.789 (0.599-1.038 n.s.
Atrial SR E (1/s) 72/1710 0.031 1.351 (1.027-1.776) n.s.
Atrial SR A (1/s) 72/1710 0.238
LASI (1/%) 72/1688 0.116 0.992 (0.982-1.002) n.s.
MV E(cm/s) 72/1693 0.219
MV A (cm/s) 72/1692 0.771
MV E/A (1/1) 72/1693 0.226
MV DT (ms) 72/1693 <0.001 1.008 (1.004-1.012) 0.002 1.007 (1.003-1.012)
E/e´ 72/1693 0.028 0.001 (0.000-0.486) 0.095 0.004 (0.000-2.477)
LA volume index (ml/m2) 72/1716 0.363
TAPSE (cm) 72/1706 0.220
TR PG median (mmHg) 54/1464 0.224
Velocity Basal Septal E (cm/s) 72/1715 0.014 1.164 (1.031-1.314) n.s.
Velocity Basal Lateral E (cm/s) 72/1715 0.042 1.097 (1.004-1.200) n.s.
Velocity Basal Septal A (cm/s) 72/1715 0.512
Velocity Basal Lateral A (cm/s) 72/1715 0.073 0.917 (0.833-1.008) n.s.
LV Stroke Vol (ml) 72/1706 0.183 0.992 (0.981-1.004) n.s.
LV EF (%) 69/1543 0.432
LV EDV (ml) 72/1706 0.083 0.993 (0.985-1.001) n.s.
LV ESV (ml) 72/1706 0.101 0.986 (0.969-1.003) n.s.
LV mass Index (g/m2) 72/1704 0.434
LV ES long Strain (%) 65/1563 0.145 1.069 (0.977-1.170) n.s.
LV PL SR S (1/s) 65/1563 0.650
LV PL SR E (1/s) 65/1563 0.004 0.316 (0.145-0.688) n.s.
LV PL SR A (1/s) 65/1563 0.154 1.857 (0.793-4.345) n.s.
PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05 PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05 PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05 PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05 PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05 PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05