Table 5 Effect of high and low proBNP in Group B: participants with reduced EF
Univariate Logistic Regression Univariate Logistic Regression Univariate Logistic Regression Multiple Binary Logistic Regression Multiple Binary Logistic Regression
Cases Positive/negative 9/110
Group n p-value HR p-value HR (CI)
PACS (%) 12/161 0.031 1.110 (1.010-1.221) 0.007 1.44 (1.10-1.87)
ACS (%) 12/161 0.179 1.046 (0.979-1.118)
ATS (%) 12/161 0.038 0.947 (0.900-0.997) n.s.
Atrial SR S (1/s) 12/161 0.013 0.259 (0.089-0.755) n.s.
Atrial SR E (1/s) 12/161 0.064 2.466 (0.949-6.411) n.s.
Atrial SR A (1/s) 12/161 0.020 2.358 (1.145-4.857) n.s.
LASI (1/%) 11/156 0.666
MV E(cm/s) 11/157 0.171 0.045 (0.001-3.811) n.s.
MV A (cm/s) 11/157 0.546
MV E/A (1/1) 11/157 0.062 0.047 (0.002-1.169) n.s.
MV DT (ms) 11/59 0.285
E/e´ 11/157 0.190 0.001 (0.000-34.83) n.s.
LA volume index (ml/m2) 12/162 0.472
TAPSE (cm) 12/161 0.009 0.149 (0.035-0.627) n.s.
TR PG median (mmHg)‡ 10/136 0.139 0.938 (0.861-1.021)
Velocity Basal Septal E (cm/s) 12/161 0.227 1.210 (0.957-1.530) n.s.
Velocity Basal Lateral E (cm/s) 12/161 0.111
Velocity Basal Septal A (cm/s) 12/161 0.352
Velocity Basal Lateral A (cm/s) 12/161 0.663
LV Stoke Volume (ml) 12/162 0.042 0.966 (0.935-0.999) 0.010 0.91 (0.85-0.98)
LV EF (%) 12/162 0.056 0.922 (0.849-1.002) n.s.
LV EDV (ml) 12/162 0.381
LV ESV (ml) 12/161 0.014 1.019 (1.004-1.035) 0.011 1.06 (1.01-1.11)
LV mass Index (g/m2) 12/154 0.461
LV ES long Strain (%) 12/140 0.015 1.186 (1.034-1.360) n.s.
LV PL SR S (1/s) 12/140 0.018 21.03 (1.704-259.4) n.s.
LV PL SR E (1/s) 12/140 0.064 0.255 (0.060-1.083) n.s.
LV PL SR A (1/s) 12/140 0.210 0.267 (0.034-2.111) n.s.
PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05 PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05 PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05 PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05 PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05 PACS: peak atrial contraction strain; ACS: atrial conduit strain; ATS: atrial total strain; SR: strain rate; S: during systole; E: during early filling phase; A: during atrial contraction; LASI: left atrial stiffness index (E/E´ /LA strain); MV: mitral valve; DT: deceleration time; LA: left atrium; TAPSE: tricuspid annular plane systolic excursion; TR PG: tricuspid regurgitation peak gradient; LV: left ventricle; EF: ejection fraction; EDV: end diastolic volume; ESV: end systolic volume; ES end systolic; PL: peak longitudinal Inclusion criteria for Stepwise Wald Logistic Regression was p<0.20 Significance in the final multiple binary logistic regression: p<0.05