FUNDING
This work was supported by the projects PI15/01073 and PI18/00997 from the Health Research Fund (FIS. Instituto de Salud Carlos III. Plan Nacional de I+D+I 2013-2016) of the Carlos III Health Institute (ISCIII, Madrid, Spain) partially financed by the European Regional Development Fund (FEDER) ‘A way of making Europe’. BRS (CPII19/00002) is recipient of a Miguel Servet contract supported by the FIS. DRT has been funded by the IiSGM through its intramural programme.