Background
Streptococcal toxic shock
syndrome (STSS) is a life-threatening infection, which usually leads to
rapid deterioration of the patient’s clinical condition. The mortality
rate is approximately 30%, with elderly populations showing remarkably
worse prognosis [1, 2]. Pyrogenic toxins produced by streptococcus
induce hypercytokinemia, leading to development of a shock state. Here,
we report a case of STSS due to group G streptococcus (GGS). The patient
exhibited necrotizing fasciitis and septic shock with unstable
hemodynamics, and was successfully treated with multidisciplinary
therapy, including polymyxin B immobilized fiber column direct
hemoperfusion (PMX-DHP) and continuous hemodiafiltration (CHDF) using a
polyacrylonitrile AN69ST membrane. We obtained the patient’s written
informed consent for publication of this case report.