3. Install packages for mpMRI-based PLDC testing. 
4. In order to perform PLDC in local cohort samples, you should train a  domain adaptation (DA)  model first (see details in the next Section " Prostate lesion assessment using your local cohort mpMRI "). Put all of your well-trained model weights under ./PLDC_software/doc/weights/. Then, you can test your samples using the open-sourced system with your well-trained DA model.  
5. Begin to test your target mpMRIs. Prepare your local cohort samples, and open the executable software. Start your testing via  "Main menu" → "Start testing". The predicted results will be under the folder "./media/output/", including prostate segmentation, prostate lesion detection, and lesion malignancy results.  You can download the following prostate_exe.mp4 to learn the details if necessary.