Results
There were 181 patients who were diagnosed with ADR and 348 ADR negative. The vast majority of the patients scored “Possible” on both Liverpool assessment tool (480/529) (Table 2.) and Naranjo scale (415/529) (Table 1.). No patient scored “Definite” on the Naranjo Scale whereas 31 patients scored “Definite” on the Liverpool tool.
When both Naranjo scale and Liverpool assessment tool were correlated with investigations used to diagnose ADR, both tools showed high sensitivity but low specificity. The Liverpool tool had the higher sensitivity at 97.2% ± 2.4% compared to Naranjo scale’s 81.2% ± 5.69%. The specificities for both tests were low at 2.3% ± 1.57% and 13.2% ± 3.56% for Liverpool and Naranjo, respectively.
Positive predictive values for Liverpool and Naranjo were similar at 34.1% and 32.7%, respectively. The negative predictive values were also similar but higher for assessment tools at 61.5% for Liverpool and 57.5% for Naranjo.